Technical Data
043218
TRIM22, NT (TRIM22, RNF94, STAF50, E3 ubiquitin-protein ligase TRIM22, 50kD-stimulated trans-acting factor, RING finger protein 94, Staf-50, Tripartite motif-containing protein 22)
Description:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
TRIM22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-97 amino acids from the N-terminal region of human TRIM22.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kajaste-Rudnitski, A., et al. Amino Acids 39(1):1-9(2010)
Petersson, J., et al. Exp. Cell Res. 316(4):568-579(2010)
Ovsyannikova, I.G., et al. Hum. Genet. 127(2):207-221(2010)
Ovsyannikova, I.G., et al. J. Infect. Dis. 201(2):207-213(2010)
Gao, B., et al. Hepatology 50(2):424-433(2009)