Technical Data
044603
Bisindolylmaleimide II (BIM II)
1mg
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A (PKA).

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 2 years after receipt when stored at -20C.

CAS Number:
137592-45-1

Molecular Formula:
C27H26N4O2

Molecular Weight:
438.5
Purity: >97% (mixture of 2 isomers) (NMR)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Product Reference:
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A: M. Gassel, et al.; J. Biol. Chem. 279, 23679 (2004)


Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.