Technical Data
044700
CTRP5, globular domain, Recombinant, Human (His) (Complement C1q Tumor Necrosis Factor-related Protein 5, C1QTNF5)
10ug
Growth Factors, Cytokines Storage: 4C/-20CShipping: Blue Ice
CTRP5 (C1qTNF-related protein 5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).

Sequence:
The globular domain of human CTRP5 (aa 96-243) is fused at the N-terminus to a His-tag.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Working aliquots are stable for up to 3 months when stored at -20C.

Molecular Weight:
~16kD (SDS-PAGE)
Source: Human, E. coli
Purity: >90% (SDS-PAGE)
Concentration: ~1mg/ml
Form: Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.