Technical Data
044794
FGF-19, Recombinant, Human (Fibroblast Growth Factor 19)
10ug
Growth Factors, Cytokines Storage: 4C/-20CShipping: Blue Ice
FGF-19 (Fibroblast growth factor 19) is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

Sequence:
Signal peptide and human FGF-19 (aa 1-216) are fused at the C-terminus to a FLAG-tag.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 6 months after receipt when stored at -20C. Working aliquots are stable for up to 3 months when stored at -20C.

Molecular Weight:
~26kD (SDS-PAGE)
Source: Human, HEK 293 cells
Purity: >90% (SDS-PAGE)
Form: Supplied as a lyophilized powder from a 0.2um-filtered solution in PBS, pH 7.2.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.