Technical Data
044904
IL-17A:Fc, Recombinant, Human (Interleukin-17A, Cytotoxic T-lymphocyte-associated Antigen 8, CTLA-8)
10ug
Molecular Biology Storage: 4C/-20CShipping: Blue Ice
Interleukin-17A (IL-17A) exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblsts, the enhancement of surface expression of ICAM-1 in fibroblast, activation of NF-kappaB and costimulation of T cell proliferation. Induces stromal cells to produce proinflammatory and hematopoietic cytokines.

Sequence:
Signal peptide and the sequence of human IL-17A (aa 1-155) are fused at the C-terminus to the Fc portion of human IgG1.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Working aliquots are stable for up to 3 months when stored at -20C.

Molecular Weight:
~45kD (SDS-PAGE)
Source: Human, HEK 293 cells
Purity: >90% (SDS-PAGE)
Form: Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.