Technical Data
044945
IL-37, Recombinant, Human (His) (Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1)
10ug
Growth Factors, Cytokines Storage: 4C/-20CShipping: Blue Ice
IL-37 (IL-1F7) belongs to the IL-1 family. It binds to interleukin-18 receptor (IL-18R) but not to IL-1 receptor. It was shown to play an important role as a link between innate and adaptive immunity and it is suggested as a new player in the inflammatory and immune responses mediated by the IL-18/IL-18R axis. It was also shown to inhibit tumor growth.

Sequence:
Human IL-37 (aa 1-218) is fused at the C-terminus to a His-tag.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Working aliquots are stable for up to 3 months when stored at -20C.

Molecular Weight:
~30kD (SDS-PAGE)
Source: Human, E. coli
Purity: >90% (SDS-PAGE)
Form: Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.