Technical Data
IL-37, truncated, Recombinant, Human (His) (Interleukin-1 Family Member 7, IL-1F7, FIL1 zeta, IL-1X, Interleukin-1 Homolog 4, IL-1H4, Interleukin-1 zeta, IL-1 zeta, IL-1RP1, IL1F7, FIL1Z, IL1H4, IL1RP1)
Molecular Biology Storage: 4C/-20CShipping: Blue Ice
IL-37 (IL-1F7; IL-1H4) belongs to the IL-1 family of proteins. It binds to the interleukin-18 receptor (IL-18R) but not to the IL-1 receptor. It plays an important role as a link between innate and adaptive immunity. IL-37 is a new player in inflammatory and immune responses, mediated by the IL-18/IL-18R axis. It was shown to inhibit tumor growth.

Human IL-37 (aa 46-218) is fused at the C-terminus to a His-tag.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 6 months after receipt when stored at -20C. Working aliquots are stable for up to 3 months when stored at -20C.

Molecular Weight:
~20kD (SDS-PAGE)
Source: Human, E. coli
Purity: >95% (SDS-PAGE)
Form: Supplied as a lyophilized powder from a 0.2um-filtered solution in 50mM TRIS-Cl, pH 8.2, 150mM NaCl.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.