Technical Data
045079
Netrin-4 (beta-Netrin, Hepar-derived Netrin-like Protein)
Description:
Netrin-4 is a 628 amino acid laminin-related secreted protein that promotes neurite elongation at low concentrations but inhibits neurite extension at high concentrations. Recent evidence suggest that Netrin family members act as regulators of both neuronal and vascular growth and are implicated in controling epithelial cell branching morphogenesis in the pancreas, breast and lung. Netrin-4 inhibits proliferation of a variety of human tumor cells. Netrin-4 also induces proliferation, migration, adhesion, tube formation and survival of human lymphatic endothelial cells and seems to function as a lymphangiogenic factor contributing to tumor dissemination.

Applications:
Suitable for use in ELISA, Western Blot

Recommended Dilution:
Optimal dilutions to be determined by researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,kNely-1Highly Purified
SizeStorageShippingSourceHost
100ug4C/-20CBlue IceHumanMouse
Concentration:
1mg/ml
Immunogen:
Netrin-4 (human) (Full-length)
Purity:
>95% (SDS-PAGE)
Form
Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Specificity:
Recognizes human and mouse Netrin-4
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.