Technical Data
045251
Resveratrol (trans-3,4',5-Trihydroxystilbene, trans-Resveratrol, (E)-Resveratrol, 3,4',5-Stilbenetriol)
50mg
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Estrogen receptor agonist. Chemopreventive. Specific inhibitor of cyclooxygenase-1 (COX-1). Anti-inflammatory. Ribonucleotide reductase and DNA synthesis. Arrests cell cycle at S/G2 phase. Anticancer and antiproliferative compound. Apoptosis inducer. Protein kinase D inhibitor. Does not inhibit PKC. Autophagy inducer. Potent SIRT1 activator. Neuroprotective. Adipogenesis inhibitor. PGC-1alpha activator. Cardioprotective. Anti-diabetic. Senescence modulator. Extends lifespan.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 2 years after receipt when stored at -20C.

CAS Number:
501-36-0

Molecular Formula:
C14H12O3

Molecular Weight:
228.2
Purity: >98 (HPLC)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Product Reference:
Antioxidant activity of resveratrol in red wine: N.J. Miller & C. Rice-Evans; Clin. Chem. 41, 1789 (1995)
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease: C.R. Pace-Asciak, et al.; Clin. Chem. Acta 235, 207 (1995)
Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor: B.D. Gehm, et al.; PNAS 94, 14138 (1997)
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes: M. Jang, et al.; Science 275, 218 (1997)
Resveratrol, a remarkable inhibitor of ribonucleotide reductase: M. Fontecave, et al.; FEBS Lett. 421, 277 (1998)
Resveratrol arrests the cell division cycle at S/G2 phase transition: F.D. Ragione, et al.; BBRC 250, 53 (1998)
Antiproliferative effect of synthetic resveratrol on human breast epithelial cells: O.P. Mgbonyebi, et al.; Int. J. Oncol. 12, 865 (1998)
Resveratrol induces extensive apoptosis by depolarizing mitochondrial membranes and activating caspase-9 in acute lymphoblastic leukemia cells: J. Drrie, et al.; Cancer Res. 61, 4731 (2001)
Inhibition of protein kinase D by resveratrol: R.S. Haworth & M. Avkiran; Biochem. Pharmacol. 62, 1647 (2001)
Resveratrol-induced autophagocytosis in ovarian cancer cells: A.W. Jr. Opipari, et al.; Cancer Res. 64, 696 (2004)
Mechanism of Human SIRT1 Activation by Resveratrol: MT. Borra, et al.; J. Biol. Chem. 280, 17187 (2005)
Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?: P. Saiko, et al.; Mutat. Res. 658, 68 (2008)
Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes: S. Rayalam, et al.; Phytother. Res. 22, 1367 (2008)
Resveratrol exerts pharmacological preconditioning by activating PGC-1alpha: L. Tan, et al.; Med. Hypotheses 71, 664 (2008)
Resveratrol and chemoprevention: S.K. Goswami & D.K. Das; Cancer Lett. 284, 1 (2009) (Review)
Resveratrol: Biological and pharmaceutical properties as anticancer molecule: T.C. Hsieh & J.M. Wu; Biofactors 36, 360 (2010) (Review)
Neuroprotective properties of resveratrol in different neurodegenerative disorders: D. Albani, et al.; Biofactors 36, 370 (2010) (Review)
Resveratrol: a cardioprotective substance: J.M. Wu & T.C. Hsieh; Ann. N. Y. Acad. Sci. 1215, 16 (2011) (Review)
Anti-diabetic effects of resveratrol: T. Szkudelski & K. Szkudelska; Ann. N. Y. Acad. Sci. 1215, 34 (2011) (Review)
Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease: A. Csiszar; Ann. N. Y. Acad. Sci. 1215, 117 (2011) (Review)
Resveratrol and life extension: B. Agarwal & J.A. Baur; Ann. N. Y. Acad. Sci. 1215, 138 (2011) (Review)
Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe: D. Delmas, et al.; Curr. Med. Chem. 18, 1100 (2011) (Review)


Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.