Technical Data
045407
AS3MT, Recombinant, Human, aa1-375, His-Tag (Arsenite Methyltransferase, Methylarsonite Methyltransferase, CYT19, S-adenosyl-L-methionine:Arsenic(III) Methyltransferase)
100ug
Molecular Biology Storage: -20CShipping: Blue Ice
AS3MT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to trivalent arsenical and may play a role in arsenic metabolism.

Source:
Recombinant corresponding to aa1-375 from human AS3MT, fused to His-tag at N-terminus, expressed in E.coli.

Molecular Weight:
~44.3kD (399aa) confirmed by MALDI-TOF

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSHMAALRD AEIQKDVQTY YGQVLKRSAD LQTNGCVTTA RPVPKHIREA LQNVHEEVAL RYYGCGLVIP EHLENCWILD LGSGSGRDCY VLSQLVGEKG HVTGIDMTKG QVEVAEKYLD YHMEKYGFQA SNVTFIHGYI EKLGEAGIKN ESHDIVVSNC VINLVPDKQQ VLQEAYRVLK HGGELYFSDV YTSLELPEEI RTHKVLWGEC LGGALYWKEL AVLAQKIGFC PPRLVTANLI TIQNKELERV IGDCRFVSAT FRLFKHSKTG PTKRCQVIYN GGITGHEKEL MFDANFTFKE GEIVEVDEET AAILKNSRFA QDFLIRPIGE KLPTSGGCSA LELKDIITDP FKLAEESDSM KSRCVPDAAG GCCGTKKSC

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~44.3kD
Source: E.coli
Purity: ~90% (SDS-PAGE)
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 20% glycerol.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Sumi,D., et al. (2011) Biochem. Biophys. Res. Commun. 415 (1), 48-53 2. Watanabe,T., et al. (2011) Arch. Toxicol. 85 (6), 577-588.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.