Technical Data
045534
PHLDA1 (DT1P1B11, MGC131738, PHRIP, TDAG51, Pleckstrin homology-like domain family A member 1, Proline- and histidine-rich protein, T-cell death-associated gene 51 protein)
Description:
PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1 (1). PHLDA1 seems to be involved in the regulation of apoptosis during neuronal development and detachment-mediated apoptosis. It may be involved in translational regulation. PHLDA1 is widely expressed with highest levels in pancreas (2).

Applications:
Suitable for use in Western Blot, Immunohistochemistry, and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:10,000-50,000
Immunohistochemistry: 1:50-100
Immunocytochemistry: 1:100-250
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
TypeIsotypeCloneGrade
Mab13C97Supernatant
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to residues in human PHLDA1.
Purity:
Supernatant
Form
Supplied as a liquid in PBS, sodium azide, BSA, glycerol.
Specificity:
Recognizes human PHLDA1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res. 2005 Jan 1;33:D54-8. 2. The UniProt Consortium Reorganizing the protein space at the Universal Protein Resource (UniProt) Nucleic Acids Res. 40: D71-D75 (2012).