Technical Data
045555
FTCD (LCHC1, Formimidoyltetrahydrofolate cyclodeaminase, Formiminotetrahydrofolate cyclodeaminase)
Description:
FTCD is a folate-dependent enzyme that displays both transferase and deaminase activity. It serves to channel one-carbon units from formiminoglutamate to the folate pool. FTCD binds and promotes bundling of vimentin filaments originating from the Golgi. Defects in FTCD are the cause of glutamate formiminotransferase deficiency (FIGLU-URIA), also known as formiminoglutamicaciduria (FIGLU-uria) (1).

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000-10,000
Immunohistochemistry: 1:50-100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
TypeIsotypeCloneGrade
Mab13C54Supernatant
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanRabbit
Concentration:
Not determined
Immunogen:
Synthetic peptide corresponding to residues in human FTCD.
Purity:
Supernatant
Form
Supplied as a liquid in PBS, sodium azide, BSA, glycerol.
Specificity:
Recognizes human FTCD.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 40:D71-D75 (2012)