Technical Data
142848
BCA-1, Recombinant, Human (Beta-cell Attracting Chemokine 1, B Cell Attracting Chemokine-1, CXCL13, BLC, BLR1 Ligand)
5ug
20ug
100ug
Molecular Biology Storage: -20°CShipping: Blue Ice
B cell Attracting Chemokine-1 (BCA-1), also known as CXCL13, is expressed at high levels in lymphoid tissues such as the spleen, lymph nodes and Peyer’s patches. It has been shown to activate signaling through the receptor BLR1 (Burkitt’s lymphoma receptor 1) to chemoattract B cells.

Source:
Recombinant protein corresponding to 87aa from human BCA-1 expressed in E.coli.

Molecular Weight:
~10.3kD

Endotoxin:
1EU/ug (LAL)

Biological Activity:
The activity is determined by its ability to chemoattract BaF3 cells transfected with CXCR5 and is typically 5-20ng/ml.

AA Sequence:
VLEVYYTSLR CRVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~10.3kD
Source: E.coli
Purity: ~97% (HPLC, Reducing and non-reducing SDS-PAGE)
Form: Supplied as a lyophilized powder in 0.02% TFA. Reconstitute with sterile dH2O.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.