Technical Data
142876
Fractalkine, Recombinant, Mouse (CX3CL1, Neurotactin)
5ug
20ug
100ug
Growth Factors, Cytokines Storage: -20CShipping: Blue Ice
Fractalkine, also known as CX3CL1, is an atypical chemokine that was the first of a fourth chemokine motif (CX3C). It is thought to function as a T cell and monocyte chemotractant and is produced by non-haemopoietic cells. Fractalkine is made in a soluble and membrane bound form in activated endothelial cells which is thought to promote adhesion of leukocytes.

Source:
Recombinant protein corresponding to 76aa from human Fractalkine expressed in E.coli.

Molecular Weight:
~8.6kD

Endotoxin:
1EU/ug (LAL)

Biological Activity:
The activity is determined by the dose dependent chemotaxis of human PBMCs and is typically starting between 10-100ng/ml.

AA Sequence:
QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~8.6kD
Source: E.coli
Purity: ~98% (HPLC, Reducing and non-reducing SDS-PAGE)
Form: Supplied as a lyophilized powder. No additives. Reconstitute with sterile dH2O.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.