Technical Data
149598
BMP4, Recombinant, Human (Bone Morphogenetic Protein 4, BMP-4, Bone Morphogenetic Protein 2B, BMP-2B, BMP2B, DVR4, DVR4, MCOPS6, OFC11, ZYME)
1ug
5ug
Molecular Biology Storage: -20CShipping: Blue Ice
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36kD homodimeric glycoprotein.

Source:
Recombinant protein corresponding to human BMP-4, expressed in HeLa cells.

Biological Activity:
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.

Endotoxin:
<0.1ng/ug (1EU/ug)

AA Sequence:
HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Source: HeLa cells
Purity: ~97% (SDS-PAGE and HPLC)
Concentration: As reported
Form: Supplied as a lyophilized powder.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.