Technical Data
A0004-02M1
ABCA2 (FITC)
Description:
BCA2 is a 250kD member of the ABC-A sub-family, which is predominantly expressed in the central nervous system, ovary and macrophages. The ABCA2 molecule shares homology with ABCA1 and ABCA7 and plays an important role in lipid metabolism. ABCA2 has been associated with Alzheimer's disease, and studies suggest that ABCA2 could also be involved in drug transport and resistance of tumors to chemotherapy.

Applications:
Suitable for use in Flow Cytometry, ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Flow Cytometry: Neat-1:10, 10ul labels 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a9E17Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseRat
Concentration:
Not determined
Immunogen:
ABCA2 transfected HeLa cells.
Purity:
Purified by Protein G Chromatography.
Form
Supplied as a liquid in PBS pH7.4, 0.09% sodium azide, 1% BSA. Labeled with fluorescein isothiocyanate (FITC).
Specificity:
Recognizes murine adenosine triphosphate (ATP) binding cassette transporter 2 (ABCA2). ATP-binding cassette (ABC) transporters are a large family of conserved proteins that translocate molecules across cellular membranes.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.