Technical Data
A0004-02R3
ABCB9 (ATP-binding Cassette Sub-family B Member 9, ATP-binding Cassette Transporter 9, ABC Transporter 9 Protein, hABCB9, TAP-like Protein, TAPL, KIAA1520)
Description:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Paraffin): 3-5ug/ml. In paraffin embedded human testis shows vesiculate cytoplasm staining of primary spermatocytes.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Peptide corresponding to C-GHNEPVANGSHKA from the C-terminus of human ABCB9 (NP_062570.1; NP_062571.1; NP_982269.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:
Recognizes human ABCB9.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Zhang F, Zhang W, Liu L, Fisher CL, Hui D, Childs S, Dorovini-Zis K, Ling V. Characterization of ABCB9, an ATP binding cassette protein associated with lysosomes. J Biol Chem. 2000 Jul 28;275(30):23287-94. PMID: 10748049.