Technical Data
A0004-02S
ABCA2 (ATP Binding Cassette 2) (PE)
Description:
ATP binding cassette (ABC) transporters are a large family of conserved proteins that translocate molecules across cellular membranes. ABCA2 is a 250kD member of the ABCA subfamily, which is predominantly expressed in the central nervous system, ovary and macrophages. The ABCA2 molecule shares homology with ABCA1 and ABCA7 and plays an important role in lipid metabolism. ABCA2 has been associated with Alzheimer's disease, and studies suggest that ABCA2 could also be involved in drug transport and resistance of tumors to chemotherapy.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: Neat 10ul labels 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.

Recommended Negative Controls
RAT IgG2a Negative Control:RPE
RAT IgG2a Negative Control:RPE

Storage and Stability:
Lyophilized powder may be stored at 4C before opening. DO NOT FREEZE! Reconstitute with ddH2O. Aliquot and store at 4C. Stable at 4C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
TypeIsotypeCloneGrade
MabIgG2a9F86Affinity Purified
SizeStorageShippingSourceHost
100Tests4C Do Not FreezeBlue IceMouseRat
Concentration:
~100 tests/ml
Immunogen:
ABCA2 transfected HeLa cells.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a lyophilized powder in PBS, pH 7.2, 1% BSA, 0.09% sodium azide. Reconstitute with 1ml sterile ddH2O.
Specificity:
Recognizes murine adenosine triphosphate (ATP) binding cassette transporter 2 (ABCA2).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.