Technical Data
A0004-02T
ABCA9 (ATP Binding Cassette Sub-family A Member 9, ATP-binding Cassette Sub-family A Member 9, DKFZp686F2450, EST640918, MGC75415)
Description:
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import.

Homology: Hu(+)

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:128,000
Western Blot: 0.1-0.3ug/ml ~170kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 184kD according to NP_525022.2).
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 3 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
0.5mg/ml
Immunogen:
Peptide with sequence C-QRVVQELEMENIQD, from the internal region of the protein sequence according to NP_525022.2.
Purity:
Serum
Form
Supplied as a liquid in Tris-saline, pH 7.3. 0.5% BSA, 0.02% sodium azide.
Specificity:
Species Crossreactivity: Human.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.