Technical Data
A0007-35K
ABL2 (Y251) (Tyrosine-protein Kinase ABL2, Abelson Murine Leukemia Viral Oncogene Homolog 2, Abelson-related Gene Protein, Tyrosine Kinase ARG, ABLL, ARG)
Description:
ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. The peptide used to generate this antibody is 100% conserved between ABL2 and ABL1.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to amino acid residues surrounding Y251 of human ABL (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human ABL.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Cao, C., et al., Biochemistry 42(35):10348-10353 (2003). 2. Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003). 3. Kruh, G.D., et al., Proc. Natl. Acad. Sci. USA 87(15):5802-5806 (1990). 4. Kruh, G.D., et al., Science 234(4783):1545-1548 (1986). 5. Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002)