Technical Data
Acid Phosphatase 1 (ACP1, Adipocyte Acid Phosphotase, HAAP, Low Molecular Weight Cytosolic Acid Phosphatase, Low Molecular Weight Phosphotyrosine Protein Phosphotase, LMW-PTP, LMW-PTPase, Red Cell Acid Phosphotase 1)
ACP1 (E.C is a unique member of Phosphotyrosine Protein phosphotase family of proteins. It is ubiquitously expressed acid phosphotase functioning as an acid phosphotase and a protein tyrosine phosphotase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeletion assembly.

Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Liver lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
100ug-20CBlue IceHumanRabbit
Synthetic peptide corresponding to aa50-100 of human ACP1.
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Recognizes human Acid phosphatase 1 (ACP1). Species sequence homology: chicken, canine, mouse, orangutan, rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Wo,Y.Y., McCormack,A.L., Shabanowitz,J., Hunt,D.F., Davis,J.P., Mitchell,G.L. and Van Etten,R.L. Sequencing, cloning, and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase J. Biol. Chem. 267 (15), 10856-10865 (1992) 2. Bottini 277 (27), 24220-24224 (July 5, 2002) 3. Giannoni JBC 278 (38), 36763-36776 (September 19, 2003).