Technical Data
A0570-50
Acid Sensitive Ion Channel beta (ASIC beta)
Description:
Two proton-gated channels, acid-sensing ionic channel (ASIC) and dorsal root ASIC (DRASIC), are known to be expressed by sensory neurons. These types of channels are of interest because low pH causes pain. ASIC Beta, a splice variant of ASIC, is found only in a subset of small and large diameter sensory neurons and is absent from sympathetic neurons or the central nervous system..

Positive Control: Rat spinal cord. Staining was blocked by preabsorption with the cognate peptide.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabSerum
SizeStorageShippingSourceHost
50ul-20CBlue IceRatGuinea pig
Concentration:
Not determined
Immunogen:
Residues 3-18 of rat ASIC Beta. AGSELDEGDDSPRDLV.
Purity:
Serum
Form
As reported
Specificity:
Reacts with rat ASIC Beta. Species Crossreactivity: This antibody reacts with rat ASIC Beta. Other species have not been tested.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Chen, C.C., et al. A sensory neuron-specific, proton-gated ion channel. PNAS USA. 95: 10240-5, 1998.