Technical Data
A0576-03A
Acid Sensitive Ion Channel 3 (ASIC3, DRASIC, Dorsal Root Ganglion ASIC)
Description:
Cellular Localization: Plasma membrane

Positive Control: ASIC3 transfected cells and primary neuronal cells.

Applications:
Suitable for use in Immunohistochemistry (Fr) and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ul-20CBlue IceRatGuinea pig
Concentration:
Not determined
Immunogen:
Synthetic peptide: TASLDPDDFDPEPSDPLGSP, corresponding to amino acids 285-304 of extracellular domain of Rat ASIC3.
Purity:
Purified by immunoaffinity chromatography.
Form
1% BSA, PBS. pH 7.4
Specificity:
Species Crossreactivity: Crossreacts with Rat.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Sutherland SP et al. Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons. Proc Natl Acad Sci U S A 98:711-6 (2001).