		Technical Data
A0667-19A	ACOX1, CT (Peroxisomal Acyl-coenzyme A Oxidase 1, Acyl-coenzyme A Oxidase 1, Peroxisomal, Palmitoyl-CoA Oxidase, AOX, Straight-chain Acyl-CoA Oxidase, SCOX, ACOX)

Description:
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.25mg/ml

Immunogen:

Synthetic peptide selected from the C-terminal region of human ACOX1 (KLH).

Purity:

Purified by Protein G affinity chromatography.

Form

Supplied as a liquid in PBS, 0.09% sodium azide.

Specificity:

Recognizes human ACOX1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1.Strausberg, R.L., et al., Proc. Natl. Acad. Sci. USA 99(26):16899-16903 (2002). 2. Chu, R., et al., J. Biol. Chem. 270(9):4908-4915 (1995). 3. Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198(3):1113-1118 (1994). 4. Fournier, B., et al., J. Clin. Invest. 94(2):526-531 (1994). 5. Varanasi, U., et al., Proc. Natl. Acad. Sci. USA 91(8):3107-3111 (1994).