Technical Data
ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.

Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry (FFPE): 1:250-1:500. Heat induced antigen retrieval in citrate buffer, pH 6.0 is required
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

PabIgGAffinity Purified
250ul-20CBlue IceHumanRabbit
As Reported
Synthetic peptide corresponding to human ACTH at the N-terminal.
Purified by immunoaffinity chromatography.
Supplied as a liquid in 10mM PBS, pH 7.4, BSA, sodium azide.
Recognizes human ACTH.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.