Technical Data
A0758-06
ACTH, CT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)
Description:
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.

Applications:
Suitable for use in ELISA, Immunohistochemistry and Immunocytochemistry. Other applications have not been tested.

Recommended Dilutions:
Immunohistochemistry: Formalin-fixed paraffin embedded sections.
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG12Q2137Affinity Purified
SizeStorageShippingSourceHost
1mg-20CBlue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
ACTH, conjugated to BSA
Purity:
Purified by Protein A affinity chromatography
Form
Supplied as a liquid in PBS, 0.1% sodium azide
Specificity:
Recognizes human CLIP (17-39 ACTH). No crossreaction with Synacthen (1-24 ACTH). Species Crossreactivity: rat C-terminal ACTH.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.