Technical Data
A0855-78C
ABR (Active Breakpoint Cluster Region-related Protein)
Description:
ABR is a GTPase-activating protein for RAC and CDC42. It promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. There are two isoform, long (98kD) and short (94kD).

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to CELKRNTLYFSTDV, from the C-terminus of the protein sequence according to NP_001083; NP_068781.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes ABR. This antibody is expected to recognize both human isoforms of this protein (as represented by NP_001083 and NP_068781).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Heisterkamp N, Morris C, Groffen J. ABR, an active BCR-related gene. Nucleic Acids Res. 1989 Nov 11;17(21):8821-31. PMID: 2587217