Technical Data
A0859-20D
ADAM 10 (Kuzbanian, KUZ, MADM, a Disintegrin and Metalloprotease 10) (APC)
Description:
ADAM10 is a transmembrane multiple domain protein with ubiquitous expression. The metalloprotease activity of ADAM10 can cleave several molecules including Notch, pro-TNF-alpha, amyloid precursor protein, myelin basic protein, and type IV collagen.

Applications:
Suitable for use in Flow Cytometry Other applications not tested.

Recommended Dilution:
Flow Cytometry: 10ul (neat) per 1 x 10e6 cells
Optimal dilution to be determined by the researcher.

Storage and Stability:
May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
TypeIsotypeCloneGrade
MabIgG2b9H28Purified
SizeStorageShippingSourceHost
100Tests4°C Do Not FreezeBlue IceHumanMouse
Concentration:
~0.01mg/ml
Immunogen:
Mouse myeloma cell line NS0­derived recombinant human ADAM10 (aa Thr214­Glu672; UniProt Accession #O14672)
Purity:
Purified
Form
Supplied as a liquid in saline, containing up to 0.5% BSA and 0.1% sodium azide. Conjugated to Allophycocyanin (APC).
Specificity:
Recognizes human ADAM10 (APC).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.