Technical Data
A0876-45
Adenovirus
Description:
Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract.The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease.

Application(s):
Suitable for use in Immunohistochemistry (Frozen) and ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilution to be determined by the researcher.

Storage and Stability:
Store at +4oC or at -20oC Immunofluorescence preferred.Storage in frost free freezers is not recommended.
TypeIsotypeCloneGrade
MabIgG2a4i302Affinity Purified
SizeStorageShippingSourceHost
500ug-20°CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Adenovirus type 3 (ATCC strain VR847)
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes all Adenovirus serotypes; binding to the hexon polypeptide. No crossreactions are known.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
General: This product has been used in: De Jong JC et al. Adenoviruses from human immunodeficiency virus-infected individuals, including two strains that represent new candidate serotypes Ad50 and Ad51 of species B1 and D, respectively. J Clin Microbiol 37:3940-5 (1999). Maddox A et al. Adenovirus infection of the large bowel in HIV positive patients. J Clin Pathol 45:684-8 (1992).