Technical Data
A0891-01A
Acrp30 (Adipocyte Complement-related Protein of 30kD, Adiponectin, AdipoQ, apM1, Gelatin Binding Protein 28, GPB28)
Description:
Adiponectin, (also known as Acrp30) is a 244 amino acid major adipokine secreted into the bloodstream from adipose tissue to modulate metabolism, including glucose regulation and fatty acid catabolism. Unlike most other adipokines, adiponectin is secreted exclusively by differentiating adipocytes at reduced levels during obesity. The serum level of adiponectin is inversely correlated with BMI (body mass index) of an individual, and has an anti-inflammatory action, playing an important role in type II diabetes (insulin sensitivity) and atherosclerosis.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Matched Pair:
Capture: A0891-01B
Detection: A0891-01A

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
MabIgG2a9E20Affinity Purified
SizeStorageShippingSourceHost
200ug4C (-20C Glycerol)Blue IceHumanMouse
Concentration:
~1mg/ml
Immunogen:
Recombinant human adiponectin purified from E coli.
Purity:
Purified by Protein A chromatography.
Form
Supplied as a liquid in PBS, pH7.4, 0.09% sodium azide.
Specificity:
Recognizes human adiponectin.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Lihn, A.S. et al. (2005) Adiponectin: action, regulation and association to insulin sensitivity. Obes. Rev. 6: 13-21. 2. Trayhurn, P. and Wood, I.S. (2005) Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem. Soc. Trans. 33: 1078-1081.