Technical Data
A0902-01E
ADP Ribosylation Factor 6, aa1-175, Recombinant, Human (ARF6, DKFZp564M0264)
100ug
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Technical Data |
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A0902-01E |
ADP Ribosylation Factor 6, aa1-175, Recombinant, Human (ARF6, DKFZp564M0264) |
100ug |
| Molecular Biology | Storage: -20°CShipping: Blue Ice |
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ADP-ribosylation factor 6, also known as ARF6, is a member of the ADP ribosylation factor family of GTP-binding proteins. It is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. Additionally, ARF6 play a central role in maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D. Source: Recombinant corresponding aa1-175 of human ARF6, fused to His-tag at N-terminus, expressed in E. coli (NP_001654). Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKLKLGQSVT TIPTVGFNVE TVTYKNVKFN VWDVGGQDKI RPLWRHYYTG TQGLIFVVDC ADRDRIDEAR QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGD GLYEGLTWLT SNYKS Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 22.2kD |
Purity: ~95% (SDS-PAGE) Concentration: ~1mg/ml Form: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 2mM DTT, 20% glycerol, 0.2mM PMSF. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Amor J C., et al. (1994) Nature. 372:704-708. 2. Randazzo P A., et al. (1994) J Biol Chem. 269:29490-29494.
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