Technical Data
ADRB2 (S364) (ADRB2R, ADRBR, B2AR, BAR, Beta-2 Adrenergic Receptor, Beta-2 Adrenoceptor, Beta-2 Adrenoreceptor, BETA2AR, Adrenergic, beta-2-, Receptor, Surface)
ADRB2, beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein is intronless.

Suitable for use in ELISA, Western Blot, Flow Cytometry, and Immunohistochemistry. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:1000
Flow Cytometry: 1:10-1:50
Immunohistochemistry (FFPE): 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As Reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 345-373 of human BAR2, UniProt Accession #P07550; NP_000015.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes human BAR2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Kobilka B.K., Dixon R.A.F.Proc. Natl. Acad. Sci. USA 84:46-50(1987) 2. Emorine L.J., Marullo S.Proc. Natl. Acad. Sci. USA 84:6995-6999(1987) 3 .Kobilka B.K., Frielle T.J. Biol. Chem. 262:7321-7327(1987).