Technical Data
Adrenocorticotrophic Hormone (ACTH, Corticotropin)
Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a polypeptide tropic hormone produced and secreted by the anterior pituitary gland. It is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of corticosteroids. A deficiency of ACTH is a cause of secondary adrenal insufficiency and an excess of it is a cause of Cushing's disease.

Suitable for use in ELISA. Other applications not tested.

Recommended Dilutions:
ELISA: 1:6400 (0.1562ug/ml)
Optimal dilutions to be determined by the researcher.

Amino Acid Sequence:

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. .
PabIgGAffinity Purified
400ug-20CBlue IceHumanRabbit
~1mg/ml (after reconstitution)
Synthetic peptide corresponding to aa1-24 of human ACTH.
Purified by Protein A affinity chromatography.
Supplied as a lyophilized powder from PBS, pH 7.4. Reconstitute with 400ul sterile PBS.
Recognizes human ACTH (aa1-24) and (aa6-24). Cross-reactivity: ACTH 1-24, ACTH 6-24, ACTH (human): 100%; ACTH 1-17: 87%; ACTH 18-39, ACTH 1-1, a-MSH (human): 0%
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.