Technical Data
A1059-70
AHA1, Recombinant, Human (Activator of Hsp90 ATPase 1, 19-337)
50ug
Molecular Biology Storage: -20CShipping: Blue Ice
The co-chaperone Aha1 (Activator of HSP90 ATPase-1) binds the middle domain of Hsp90 (amino acid 272-627) and is proposed to function as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. Recombinant Aha1 was expressed in E. coli and purified by using conventional chromatography techniques.

Sequence:
MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL
IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK
EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA
RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV
SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ
GWQRYYFEGI KQTFGYGARL

Storage and Stability:
For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
36.1kD
Source: Recombinant, Human from E. coli
Purity: Chromatographically purified, 95% by SDS-PAGE
Concentration: ~1mg/ml
Form: Supplied as a liquid in 20mM Tris pH 8, 2mM EDTA.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Meyer P., et al (2004). EMBO 23(6) : 1402-10 2. Siligardi G ., et al (2004). J Biol Chem. 270(50) : 51989-98

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.