Technical Data
A1059-70
AHA1, Recombinant, Human (Activator of Hsp90 ATPase 1, 19-337)
50ug
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Technical Data |
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A1059-70 |
AHA1, Recombinant, Human (Activator of Hsp90 ATPase 1, 19-337) |
50ug |
| Molecular Biology | Storage: -20°CShipping: Blue Ice |
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The co-chaperone Aha1 (Activator of HSP90 ATPase-1) binds the middle domain of Hsp90 (amino acid 272-627) and is proposed to function as an ATPase-activating protein that competes with p23 and other co-chaperones for Hsp90 binding. Recombinant Aha1 was expressed in E. coli and purified by using conventional chromatography techniques. Sequence: MATNVNNWHW TERDASNWST DKLKTLFLAV QVQNEEGKCE VTEVSKLDGE ASINNRKGKL IFFYEWSVKL NWTGTSKSGV QYKGHVEIPN LSDENSVDEV EISVSLAKDE PDTNLVALMK EEGVKLLREA MGIYISTLKT EFTQGMILPT MNGESVDPVG QPALKTEERK AKPAPSKTQA RPVGVKIPTC KITLKETFLT SPEELYRVFT TQELVQAFTH APATLEADRG GKFHMVDGNV SGEFTDLVPE KHIVMKWRFK SWPEGHFATI TLTFIDKNGE TELCMEGRGI PAPEEERTRQ GWQRYYFEGI KQTFGYGARL Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Molecular Weight: 36.1kD |
Source: Recombinant, Human from E. coli Purity: Chromatographically purified, 95% by SDS-PAGE Concentration: ~1mg/ml Form: Supplied as a liquid in 20mM Tris pH 8, 2mM EDTA. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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1. Meyer P., et al (2004). EMBO 23(6) : 1402-10 2. Siligardi G ., et al (2004). J Biol Chem. 270(50) : 51989-98
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