Description:
Applications: Suitable for use in Western Blot. Other applications have not been tested.
Recommended Dilution: Optimal working dilutions to be determined by researcher.
Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
| Type | Isotype | Clone | Grade |
| Pab | IgG | | Affinity Purified |
|
| Size | | Storage | Shipping | Source | Host |
| 100ug | | -20°C | Blue Ice | Human | Rabbit |
|
| Concentration: |
| ~5mg/ml |
| Immunogen: |
| Peptide corresponding to amino acids 593 - 606 of human AIF (CT). |
| Purity: |
| Purified IgG was prepared from whole serum by affinity chromatography. |
| Form |
| Supplied as a liquid in PBS with 0.02% sodium azide. |
| Specificity: |
| Recognizes apoptosis inducing factor (AIF). The antibody reacts with the C-terminal region of the AIF. AIF is widely expressed in human tissues and localizes in the mitochondria. AIF translocates to the nucleus upon induction of apoptosis. Species Crossreactivity: Mouse, Rat |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
1. Susin. S.A. et al. (1999). Molecular characterization of mitochondrial apoptosis - inducing factor. Nature. 397: 441-6. |
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