Technical Data
A1334-39J
ALDH18A1, ID (Delta-1-pyrroline-5-carboxylate Synthase, P5CS, Aldehyde Dehydrogenase Family 18 Member A1, GSAS, P5CS, PYCS)
Description:
ALDH18A1 is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the Center region of human ALDH18A1 (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human ALDH18A1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Hu,C.A., et.al., Amino Acids 35(4), 665-672 (2008). 2. Bicknell,L.S., et.al., Eur. J. Hum. Genet. 16(10), 1176-1186 (2008).