Technical Data
A1363-01B
ALS2CR1 (Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 1 Protein, NIF3-like Protein 1, NIF3L1, MDS015, My018)
Description:
Amyotrophic lateral sclerosis chromosomal region candidate gene protein 1 (ALSCR1) or NIF3-like protein1 is a 39kD cytoplasmic protein that participates in neuronal differentiation. The ALS2CR1 full-lengh transcrip is encoded within the ALS2 critical region, however, experimental evidences indicate that ALS2CR1 is not causative gene for amyotrophic lateral sclerosis (ALS20).

Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 0.2-1ug/ml
Immunohistochemistry (paraffin): 2-4ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human heart lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to CILSETDRDPLQVV, from the C-terminus of the protein sequence according to NP_068596.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human ALS2CR1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Tascou S, Uedelhoven J, Dixkens C, Nayernia K, Engel W, Burfeind P. Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals. Cytogenet Cell Genet. 2000;90(3-4):330-6. PMID: 11124544.