Technical Data
A1378-25A
ATIC, CT (Bifunctional Purine Biosynthesis Protein PURH, Phosphoribosylaminoimidazolecarboxamide Formyltransferase, 5-aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase, AICAR Transformylase, IMP Cyclohydrolase, Inosinicase, IMP Synthetase, OK/
Description:
ATIC is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity.

Applications:
Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceHumanRabbit
Concentration:
~0.25mg/ml
Immunogen:
Synthetic peptide selected from the C-terminal region of human ATIC (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human ATIC.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Vergis,J.M., et.al., J. Biol. Chem. 276(11), 7727-7733 (2001).