Technical Data
A1378-36M
5-Aminoisoquinolinone Hydrochloride (5-AIQ)
1mg
5mg
Molecular Biology Storage: 4CShipping: RT
Water-soluble, potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1).

Solubility:
DMSO, H2O: 20mg/ml

CAS Number:
93117-07-8

Molecular Formula:
C9H8N2OHCl

Molecular Weight:
160.2
Purity: 97%
Form: Beige to brown powder.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock: M.C. McDonald, et al.; Br. J. Pharmacol. 130, 843 (2000)
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury: S. Cuzzocrea, et al.; Biochem. Pharmacol. 63, 293 (2002)
Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation: H. Kleine, et al.; Mol. Cell 32, 57 (2008)

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.