Technical Data
A1378-36M
5-Aminoisoquinolinone Hydrochloride (5-AIQ)
1mg
5mg
5mg
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Technical Data |
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A1378-36M |
5-Aminoisoquinolinone Hydrochloride (5-AIQ) |
1mg 5mg |
| Molecular Biology | Storage: 4°CShipping: RT |
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Water-soluble, potent inhibitor of poly(ADP-ribose) polymerase-1 (PARP-1). Solubility: DMSO, H2O: 20mg/ml CAS Number: 93117-07-8 Molecular Formula: C9H8N2O•HCl Molecular Weight: 160.2 |
Purity: 97% Form: Beige to brown powder. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock: M.C. McDonald, et al.; Br. J. Pharmacol. 130, 843 (2000) Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury: S. Cuzzocrea, et al.; Biochem. Pharmacol. 63, 293 (2002) Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation: H. Kleine, et al.; Mol. Cell 32, 57 (2008)
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