Technical Data
A1585-02
Amphiregulin (Amphiregulin Precursor, AR, AREG, Colorectum Cell-derived Growth Factor, CRDGF, MGC13647, Schwannoma-derived Growth Factor, SDGF)
Description:
AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
1ml4C/-20C (No Glycerol)Blue IceHumanRabbit
Concentration:
~5mg/ml
Immunogen:
Synthetic peptide, VKPPQNKTESENTSDKPKR, corresponding to the aa108-126 of the native molecule conjugated to KLH.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human AMPHIREGULIN.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.