Technical Data
A1585-02A
Amphiregulin, CT (AREG, Colorectum Cell-derived Growth Factor, AREGB, AR, SDGF, CRDGF, MGC13647)
Description:
AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the C-terminal region of human AREG (KLH).
Purity:
Purified by ammonium sulfate precipitation.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human AREG.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Shim,J.Y., J. Korean Med. Sci. 23(5), 857-863 (2008). 2.Eckstein,N., J. Biol. Chem. 283(2), 739-750 (2008). 3.Revillion,F., Ann. Oncol. 19(1), 73-80 (2008). 4.Kimura,H., Nature 348(6298), 257-260 (1990).