Technical Data
A2230
Amphotericin B Solution, 100X (Fungizone, Fungilin, Ampho-Moronal)
100ml
Biochemicals Storage: -20CShipping: Blue Ice
Amphotericin B is a polyene antifungal agent for yeast, mold and mycoplasma. It was first isolated by Gold, et a., from Streptomyces nodosus in 1955. It is an amphoteric compound composed of a hydrophilic polyhydroxyl chain along one side and a lipophilic polyene hydrocarbon chain on the other. Amphotericin B is poorly soluble in water. Amphotericin B binds to sterols, preferentially to the primary fungal cell membrane sterol, ergosterol. This binding disrupts osmotic integrity of the fungal membrane, resulting in leakage of intracellular potassium, magnesium, sugars, and metabolites and then cellular death.

Used in the preparation of baculoviral stocks.

Form:
Supplied as an easy to use 100X concentrate.

pH: 10-12

Activity: 250ug/ml

Sterility:
Aseptically prepared by 0.2um filtration

Usage:
Add aseptically 1ml concentrate to 100ml culture medium.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C.

CAS Number:
1397-89-3

Molecular Formula:
C47H73NO17

Molecular Weight:
924.09
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.