		Technical Data
A2293-08	ANGPT1, NT (Angiopoietin-1, ANG-1, KIAA0003)

Description:
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in early heart development.

Applications:
Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2000
ELISA: 1:5000-1:25,000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Serum

Size		Storage	Shipping	Source	Host
50ul		-20°C	Blue Ice	Mouse	Rabbit

Concentration:

Not determined

Immunogen:

Synthetic peptide corresponding to aa21-40 of mouse ANGPT1 at N-terminal (KLH).

Purity:

Serum

Form

Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.

Specificity:

Recognizes mouse ANGPT1. Species sequence homology: human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.