Technical Data
A2293-48K
ANGPTL3, NT (Angiopoietin-related Protein 3, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5, UNQ153/PRO179, ANGPT5)
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Technical Data |
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A2293-48K |
ANGPTL3, NT (Angiopoietin-related Protein 3, Angiopoietin-like Protein 3, Angiopoietin-5, ANG-5, UNQ153/PRO179, ANGPT5) |
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Description: ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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