Technical Data
A2293-48T
Angptl4 (Angiopoietin-related Protein 4, 425O18-1, Angiopoietin-like Protein 4, Fasting-induced Adipose Factor, Hepatic Fibrinogen/Angiopoietin-related Protein, HFARP, Secreted Protein Bk89, Farp, Fiaf, Ng27)
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Technical Data |
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A2293-48T |
Angptl4 (Angiopoietin-related Protein 4, 425O18-1, Angiopoietin-like Protein 4, Fasting-induced Adipose Factor, Hepatic Fibrinogen/Angiopoietin-related Protein, HFARP, Secreted Protein Bk89, Farp, Fiaf, Ng27) |
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Description: Angiopoietin-like protein 4 (ANGPTL4), also known as PPAR angiopoietinrelated protein, fasting-induced adipose factor, or hepatic fibrinogen /angiopoietin-related protein (HFARP), is a secreted adipokine predominantly expressed in adipose tissue and liver. The experimental results show that ANGPTL4 is a blood-borne hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. Serum levels of ANGPTL4 were decreased in patients with type 2 diabetes. In animal experiments, ANGPTL4 treatments might reduce hyperglycemia, and improve glucose tolerance by decreasing hepatic glucose production and enhancing insulin-mediated inhibition of gluconeogenesis. However, the molecular mechanisms underlying its metabolic actions remain elusive. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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