Technical Data
A2293-52E
ANGPTL7 (Angiopoietin-related Protein 7, Angiopoietin-like Protein 7, Angiopoietin-like Factor, Cornea-derived Transcript 6 Protein, CDT6, UNQ313/PRO35)
Description:
Angiopoietin-like Factor (ANGPTL7), also known as cornea-derived transcript 6 (CDT6), is a secreted 45kD protein that contains a coiled-coil domain (aa30-110) and a fibrinogen-like domain (aa113-334). ANGPTL7 is expressed in the stromal layer of the cornea, and it forms disulfide-linked homotetramers. It contributes to corneal morphogenesis by suppressing angiogenesis and promoting the deposition of extracellular matrix components. ANGPTL7 is up-regulated in glaucoma and accumulates in the aqueous humor. Mature mouse ANGPTL7 shares 88% and 98% sequence identity with human and rat ANGPTL7.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Direct ELISA: 0.5-1ug/ml
Western Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouseGoat
Concentration:
Not determined
Immunogen:
Recombinant corresponding to mouse ANGPTL7 expressed in NSO cells (Q8R1Q3).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a lyophilized powder in PBS with 5% trehalose. Reconstitute with sterile PBS.
Specificity:
Recognizes mouse ANGPTL7.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.