Technical Data
A2294-48W
Angiotensin I (Angiotensin-1, Ang I)
Description:
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilutions:
ELISA: 1:32,000 (0.0312ug/ml)
Optimal dilutions to be determined by the researcher.

Amino Acid Sequence:
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
400ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml (after reconstitution)
Immunogen:
Synthetic peptide corresponding to human Angiotensin I.
Purity:
Purified by Protein A affinity chromatography
Form
Supplied as a lyophilized powder. Reconstitute with 400ul sterile ddH2O.
Specificity:
Recognizes human Angiotensin I. Species Crossreactivity: rat, mouse, and canine. Does not recognize human Angiotensin II or III.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.