Technical Data
A2295-13B1
Anion Exchanger 2 (AE-2)
Description:
Human AE2 gene (chromosome 7q35-q36) encodes a protein of 1241 aa (mouse 1237 aa, rat 1234 aa). Several isoforms of AE2 are also expressed as a result of alternative splicing. AE2 is widely expressed in many tissues.

Applications:
Suitable for use in ELISA, Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1-10ug/ml using ECL.
ELISA: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.

Control Peptide:
A2295-14D1 Anion Exchanger 2, Rat Control Peptide (AE2)

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ug4C (-20C Glycerol)Blue IceRatRabbit
Concentration:
~1mg/ml
Immunogen:
A 21 AA Peptide sequence near the N-terminus of rat AE-2 (KLH).
Purity:
Purified by affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, 40% glycerol.
Specificity:
Recognizes rat Anion Exchanger 2. Species Crossreactivity: mouse. Species sequence homology: rabbit (90%), human (85%), chicken (80%).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Negrini C et al (1995) BBA 1236, 207; Chow A et al (1992) Am J Physiol. 263, G345; Kudrycki KE et al (1990) J Biol. Chem. 265, 462; Kopito et al (1990) Intl. Rev. Cytol. 123, 177; Lindsey AE et al (1990) PNAS 87, 3456; Alper et al (1988) J Biol. Chem. 263, 17092; Demuth DR et al (1986) EMBO J., 5, 1205.