		Technical Data
A2295-19Q	Ankyrin repeat and SOCs box-containing protein (Asb-3)

Description:
The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain “SOCS boxes” but differ from other families of protein in the motifs they contain upstream of the SOCS box(1). SOCS boxes are carboxy-terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases.

Applications:
Western blot, positive control: human spleen whole cell lysate

Recommended Dilution:
Western blot: 1:500-1:1000

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Type	Isotype	Clone	Grade
Pab	IgG		Purified

Size		Storage	Shipping	Source	Host
200ul		-20°C	Blue Ice	Human	Rabbit

Concentration:

As reported

Immunogen:

Synthetic peptides corresponding to amino acids 63-75 and 166-180 of human Asb-3.

Purity:

Purified

Form

Supplied as a liquid in PBS, 0.1mg/ml BSA, 0.02% sodium azide.

Specificity:

Does not cross-react with mouse or rat Asb-3.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Kile BT., et al. Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. Gene. 2000 Nov 27;258(1-2):31-41. 2. Krebs DL, Hilton DJ. Stem Cells 19:378-87 (2001). 3. Wang J, Campbell IL. J Neurosci Res 67:423-7 (2002).