Technical Data
A2296-73
ANO7 (Anoctamin-7, Dresden Transmembrane Protein of the Prostate, D-TMPP, IPCA-5, New Gene Expressed in Prostate, Prostate Cancer-associated Protein 5, Transmembrane Protein 16G, NGEP, PCANAP5, TMEM16G)
Description:
NGEP is a 933aa protein belonging to the TMEM16 family and consisting of TM16H1, TM16H2 and TM16H3 domains. Artificial human TMEM16G (844T) consists of eight-transmembrane proteins. Two NGEP proteins are encoded as a result of splicing. It plays an important role in cell-cell interactions. NGEP acts as a promising immunotherapy target for prostate cancer and is highly expressed in epithelial cells of the prostate (at protein level).

Applications:
Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:100-1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGSerum
SizeStorageShippingSourceHost
100ul-20°CBlue IceHumanRabbit
Concentration:
Not determined.
Immunogen:
Synthetic peptide corresponding to aa325-342 (KWNKYQPLDHVRRYFGEK) of human NGEP.
Purity:
Serum
Form
Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Specificity:
Recognizes human ANO7. Species Crossreactivity: chimpanzee, mouse. Species sequence homology: rat, monkey, canine, bovine, chicken, opossum.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Bera, TK. et al.Proc. Natl. Acad. Sci. 101:3059-3064 (2004). 2. Katoh, M. et al. Int. J. Mol. Med. 14:759-764 (2004).